Name: FORMALINE 4500ml
Brand: SHRI GAUTAM CHEMICALS
SKU: AMC-FML-FHD-4500-
Availability: InStock

FORMALINE 4500ml

Formalin (Formaldehyde Solution USP, 4500 ml) is a laboratory-grade chemical used for disinfection, sterilization, and biological specimen preservation. It contains approximately 37–40% formaldehyde gas dissolved in water and is manufactured by Shri Gautam Chemicals in Jaipur.

✅ Applications

Tissue Fixation: Used in histopathology labs to preserve biological specimens
Surface Disinfection: Effective for cleaning lab surfaces and equipment
Sterilization: Occasionally used for fumigation in biosafety cabinets and rooms
Preservation: Maintains structural integrity of tissues for microscopic analysis

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Formalin is a 37–40% aqueous solution of formaldehyde gas, widely used as a disinfectant and preservative due to its potent antimicrobial and protein-fixing properties. It works by cross-linking proteins and nucleic acids, effectively inactivating microorganisms and stabilizing biological tissues.

🧪 Description of Formalin (Formaldehyde Solution USP)

Formalin, chemically known as formaldehyde (CH₂O) in water, is a highly reactive aldehyde that functions as both a biocide and fixative. Its mechanism of action is based on alkylation and cross-linking of cellular components, which disrupts microbial metabolism and structural integrity.

🔬 Mechanism of Action

Protein Denaturation: Formalin reacts with amino groups in proteins, forming methylene bridges that alter protein structure and function.
DNA/RNA Fixation: It binds to nucleic acids, preventing replication and transcription, which halts microbial growth.
Cell Wall Penetration: Its small molecular size allows it to penetrate microbial membranes, making it effective against a wide range of pathogens.

🧫 Antimicrobial Spectrum

Bactericidal: Effective against Gram-positive and Gram-negative bacteria
Virucidal: Inactivates enveloped and non-enveloped viruses
Fungicidal: Destroys molds and yeasts
Sporicidal: Capable of killing bacterial spores at higher concentrations or prolonged exposure

🧪 Applications in Laboratory & Clinical Settings

Tissue Preservation: Used in histopathology to fix biological specimens for microscopic examination
Surface Disinfection: Applied to disinfect work surfaces, equipment, and containers
Sterilization: Occasionally used in fumigation of rooms and biosafety cabinets

⚠️ Safety Considerations

Toxicity: Formalin is a known irritant and potential carcinogen; exposure must be minimized
Ventilation: Always use in well-ventilated areas or under fume hoods
Protective Equipment: Gloves, goggles, and lab coats are essential during handling
Disposal: Must be treated as hazardous chemical waste and disposed of according to biomedical guidelines

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